RFQMR technology has a totally
different approach from conventional therapies such as chemotherapy,
radiotherapy or surgery.This safe treatment alternative may control the tumor growth process
through its effect in the cell division mechanism. It can stop tumor
activity and growth and provide relief to symptoms such as pain,
lack of appetite and weight loss.
The Cytotron is having significant impact in the treatment of
cancer and osteoarthritis in Asia & Europe, as evidenced by some
recently concluded clinical studies. In cancer, an all comer,
compassionate Phase I clinical trial was conducted in Bangalore,
India, to treat terminally ill cancer patients with metastatic
/end-stage disease, as well as degenerative diseases such as
osteoarthritis. RFQMR is a safe, affordable and effective
treatment alternative that uses very low frequency, non-ionizing,
non thermal electromagnetic waves in the radio or sub-radio
frequencies. In cancer, these waves are hypothetically believed to
trigger programmed cell death and stop tumor growth through its
effects on cell division. It is crucial to leverage the prevailing
state of the art genome-wide or pathway specific molecular
technologies (mutational analysis, gene expression profiling and
biomarker identification) to study the near and long term effects
and the mechanism of action of RFQMR in human tissues. This can be
enabled using in-vitro, in-vivo and ex-vivo systems of
tumor stem cells, multiple cell types, cell lines, tissue and
organ explants, human tumor xenografts, and other animal model
systems of disease. Parallel clinical studies need to be conducted
to expand the application of RFQMR to primary cancer and other
disease indications like pain management, macular degeneration,
tissue regeneration and wound healing, to name a few.. There is
on-going R&D for other indications such as multiple sclerosis,
macular degeneration, diabetic neuropathy & targeted drug
delivery, to name a few.
Focused Resonance
Nanopermeabilization or FORN, could be defined as
combined antitumor treatment that consists of systemic or local
administration of cytotoxic drug (e.g. chemotherapy) followed by
focused resonance radio frequency pulses delivered to the tumor or
the whole body using specially designed delivery system. All cells
and tissue, cancer or otherwise have a specific resonance
frequency dependant on the density or concentration of hydrogen
atoms in a group of these (similar) cells. When these cells are
placed in a high instantaneous magnetic field, the protons in them
get oriented. At this moment if a radio frequency pulse close to
the resonating frequency of the cell colony is fired, these cells
start attaining the beat frequency. As the frequency gets closer
and closer to the resonating frequency, the resultant frequency
remains constant but and the amplitude starts rising, thus
increasing the trans membrane potentials many times causing
temporary pathways which would close when the signal is removed
after the drug passes through the cell membrane. The interesting
and unique fact of this technique is that cell permeabilization
occurs only in those cells or tissues (group of cells) that are in
resonance and attain beat frequency. The non-resonating cells do
not respond to the FORN treatment, as they are in their resting
state. Consequently the main factors that play crucial role in
obtaining high responses of the FORN treatment are the drug used
in the treatment and the technique and method of creating
controlled resonance, and beating it accurately so as to increase
the membrane potential to a specific value and for a predetermined
time interval sufficient to transport the interested molecule
through the temporary pathway and deliver to the tumor.
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